05/07/08 Acucela Files Investigational New Drug Application -- Orally-available Small Molecule for Dry Form of AMD 04/29/08 Acucela Presents Preclinical Data from Retinopathy Study Demonstrating Improvement in Retinal Abnormalities 04/22/08 Acucela Announces Presentation of Data in Preclinical Study of Retinopathy 03/18/08 Acucela to Present at INVEST NORTHWEST 2008 Conference 10/16/07 Acucela Paper Published in Experimental Eye Research 10/09/07 Award of Phase I SBIR Grant from NIH 10/08/07 Appointment of Deborah A. Kessler as Chief Operating Officer 08/21/07 Acucela Announces Screening Collaboration To Identify Novel Drugs For Macular Degeneration 06/11/07 Acucela Awarded NIH/SBIR Grant for Environmental Retinal Toxicology Program 04/05/07 Biotech Company Acucela Inc. Secures $25M in Additional Financing 01/27/07 Acucela Paper Published in Investigative Ophthalmology and Visual Science 09/06/06 Acucela to Participate at BioJapan World Business Forum 07/14/06 Acucela Paper Published in Investigative Ophthalmology and Visual Science 07/12/06 Acucela Presents at ARVO Summer Conference on Macular Degeneration 04/28/05 Acucela Inc. Adds to Board of Directors 04/21/05 Acucela Inc. Hires Seasoned Clinical Development Team 11/24/04 Acucela Inc. Secures $13.4 M in Series B Financing 11/22/04 Acucela Leading Ophthalmology Researcher to Join Acucela's Scientific Advisory Board 08/04/04 Pharmaceutical Executive to Join Acucela's Scientific Advisory Board 06/30/04 Acucela Inc. Forms Collaboration with Dr. Michael Kahn and the Institute for Chemical Genomics 06/20/04 Olympus and Acucela Inc. Extend Collaboration 04/26/04 Toyama Chemical Co., Ltd., and Acucela Inc. Enter into Collaboration for Potential Ophthalmic Treatments 09/04/03 UW Signs Licensing Agreement for Study of Eye Disease 09/04/03 Asahi News: "Former Assistant Professor of the University of Washington Starts Pharmaceutical Venture Company" 07/25/03 Olympus Optical and Acucela Inc. Form Collaboration 06/25/03 Nikkei Sangyo News: "Long Term Culture of Neuronal Cells Used in Efficacy Testing for New Drugs"